Study Shows How Cells Could Help Artemis Astronauts Exercise

NASA’s Orion spacecraft will carry astronauts further into space than ever before using a module based on Europe’s Automated Transfer Vehicles (ATV). Credit: NASA

In 2033, NASA and China plan to send the first crewed missions to Mars. These missions will launch every two years when Earth and Mars are at the closest points in their orbits (Mars Opposition). It will take these missions six to nine months to reach the Red Planet using conventional technology. This means that astronauts could spend up to a year and a half in microgravity, followed by months of surface operations in Martian gravity (roughly 40% of Earth gravity). This could have drastic consequences for astronaut health, including muscle atrophy, bone density loss, and psychological effects.

Aboard the International Space Station (ISS), astronauts maintain a strict exercise regimen to mitigate these effects. However, astronauts will not have the same option while in transit to Mars since their vehicles (the Orion spacecraft) have significantly less volume. To address this challenge, Professor Marni Boppart and her colleagues at the Beckman Institute for Advanced Science and Technology are developing a process using regenerative cells. This work could help ensure that astronauts arrive at Mars healthy, hearty, and ready to explore!

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Want to Stay Healthy in Space? Then you Want Artificial Gravity

A close up of three fruit flies, used for scientific research both on Earth and in space. Credits: NASA Ames Research Center/Dominic Hart

Space travel presents numerous challenges, not the least of which have to do with astronaut health and safety. And the farther these missions venture from Earth, the more significant they become. Beyond Earth’s protective atmosphere and magnetosphere, there’s the threat of long-term exposure to solar and cosmic radiation. But whereas radiation exposure can be mitigated with proper shielding, there are few strategies available for dealing with the other major hazard: long-term exposure to microgravity.

Aboard the International Space Station (ISS), astronauts rely on a strict regimen of exercise and resistance training to mitigate the physiological effects. These include muscle atrophy, bone density loss, organ function, eyesight, and effects on cardiovascular health, gene expression, and the central nervous system. But as a recent NASA study revealed, long-duration missions to Mars and other locations in deep space will need to be equipped with artificial gravity. This study examined the effects of microgravity on fruit flies aboard the ISS and demonstrated artificial gravity provides partial protection against those changes.

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Many Astronauts Never Recover all of their Bone Density after Returning to Earth

In his book, Endurance, astronaut Scott Kelly described the arduous task of readjusting to life on Earth after spending a year in space. As part of NASA’s Twins Study, Kelly lived and worked aboard the International Space Station (ISS) while his identical twin (astronaut Mark Kelly) remained on Earth. While the results of this study revealed how prolonged exposure to microgravity could lead to all manner of physiological changes, the long and painful recovery Kelly described in his book painted a much more personal and candid picture.

As it turns out, astronauts who spend extended periods in space may never fully recover. At least, that is the conclusion reached by an international team led by the University of Calgary after they assessed the bone strength of multiple astronauts before and after they went to space. They found that after twelve months of recovery, the astronaut’s bones had not regenerated completely. These findings could have significant implications for proposed future missions, many of which involve long-duration stays in space, on the Moon, and Mars.

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Fire Acts Strangely in Microgravity. Astronauts Have Lit More Than 1,500 Fires on the Space Station to Figure Out Why

Ever since childhood, we were all told to never play with fire. Despite it being relevant to our everyday lives, to include heating our homes and water, cooking our food, producing electricity, and more, fire is extremely dangerous. We were all indoctrinated more with how to put out fires instead of how to start one. We’ve all been told about its destructive properties if mishandled, and that fire needs to be controlled. One of the perks of adulthood, and especially being a scientist, is you get paid to play with fire. Despite fire’s complexities, there’s still a lot we don’t know about its behavior. With more and more of humanity traveling to space and living in microgravity, it’s important to learn about how fire behaves in this unique environment to better prepare ourselves for worst case scenarios. But what if we could also control fire so it’s not as dangerous and less destructive to the environment back here on Earth?

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Magnetic Chamber can Simulate Microgravity (or Mars Gravity) Here on Earth

There are plenty of processes that might be easier in lower gravity.  So far, the biggest hindrance to developing those processes has been the expense of launching equipment to the low gravity environments of the ISS or other space-based research stations.  Testing on the ground would be preferable both for ease of use and much lower cost, but the Earth’s gravity usually puts a stop to that.  Some scientists see another way. Using magnetic fields can artificially simulate a zero-gravity environment, and now a team from Florida State University’s (FSU’s) National High Magnetic Field Laboratory has developed a system that can hold a much larger sample than previous iterations.

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Every Challenge Astronauts Will Face on a Flight to Mars

Nuclear-powered transit habitat
An artist's conception shows a Mars transit habitat with a nuclear propulsion system. Credit: NASA

In 1972, the Space Race officially ended as NASA sent one last crew of astronauts to the surface of the Moon (Apollo 17). This was the brass ring that both the US and the Soviets were reaching for, the “Moonshot” that would determine who had supremacy in space. In the current age of renewed space exploration, the next great leap will clearly involve sending astronauts to Mars.

This will present many challenges that will need to be addressed in advance, many of which have to do with simply getting the astronauts there in one piece! These challenges were the subject of a presentation made by two Indian researchers at the SciTech Forum 2020, an annual event hosted by the International Academy of Astronautics (IAA), RUDN University, and the American Astronomical Society (AAS).

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Health Issues From Spaceflight Might Originate in the Mitochondria

Credit: NASA

It’s not easy living and working in space for extended periods of time. As NASA’s Twins Study illustrated, microgravity takes a toll on human physiology, which is followed by a painful transition back to normal gravity (just ask Scott Kelly!) Aside from muscle and bone degeneration, there’s diminished organ function, effects on cardiovascular health, the central nervous system, and “subtle changes” on the genetic level.

Until now, the biggest unanswered question was what the underlying cause of these physical impacts was. But after reviewing all of the data accumulated from decades of research aboard the International Space Station (ISS) – which included the Twins Study and DNA samples taken from dozens of astronauts – an international team of researchers came to the conclusion that mitochondria might be the driving force for these changes.

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This is Foam, Made in Space

An early image from the ESA's Foam-Coarsening on the ISS. Image Credit: ESA

Say hello to Space Foam.

The ESA has a science lab on the International Space Station called Columbus. Inside that lab is the Fluid Science Laboratory, dedicated to studying the behaviour of fluids in microgravity. Currently, that lab is being used to study a substance most of us probably don’t spend much time thinking about: foam.

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To Avoid Vision Problems in Space, Astronauts Will Need Some Kind of Artificial Gravity

The International Space Station in March 2009 as seen from the departing STS-119 space shuttle Discovery crew. Credit: NASA/ESA

Ever since astronauts began going to space for extended periods of time, it has been known that long-term exposure to zero-gravity or microgravity comes with its share of health effects. These include muscle atrophy and loss of bone density, but also extend to other areas of the body leading to diminished organ function, circulation, and even genetic changes.

For this reason, numerous studies have been conducted aboard the International Space Station (ISS) to determine the extent of these effects, and what strategies can be used to mitigate them. According to a new study which recently appeared in the International Journal of Molecular Sciences, a team of NASA and JAXA-funded researchers showed how artificial gravity should be a key component of any future long-term plans in space.

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